Cardiac manifestations in primary Sjogren's syndrome.

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Primary Sjogrens Syndrome in a Child

Sjögren syndrome is uncommon in children and occurs most often in association with autoimmune diseases (secondary Sjögren syndrome). We describe the clinical and biological features of a 7-year-old girl with primary Sjögren syndrome revealed by recurrent parotiditis. CASE REPORT A 7-year-old girl was referred for investigation of multiple episodes of parotid swelling since age 4 years, withou...

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Cardiac manifestations in primary Sjögren's syndrome.

OBJECTIVE To determine cardiac manifestations in primary Sjögren's syndrome (SS). METHODS Echocardiographic examination was undertaken in 64 patients (62 women, two men) with primary SS (54 definite (DSS) and 10 probable (PSS)) who had systemic symptoms. Twenty one healthy women volunteers of similar age acted as controls. RESULTS Acute exudative pericarditis occurred in only one patient. A...

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3431 Conjunctiva immunopathology in primary sjogrens syndrome (1° S.S.)

Aim: To evaluate the histological changes and immune response of conjuctiva in patients (pts) with lo S.S. Materials and Methods: We studied conjunctiial biopsies from 15 pts with I0 S.S. and 2 normal controls using 1) paraflfn section screening for the quality of conjunctival epithelium (CE), the number of goblet cells (GC) and the degree of inflammation, 2) Mo-abs and Pabs to: Tlymphocytes, T...

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Profiling Micro-RNA expression in patients with Primary Sjogrens Syndrome – contribution to disease pathogenesis

Background Sjogrens syndrome (SS) is a chronic autoimmune disorder, characterised by lymphocytic infiltration resulting in exocrine gland destruction and other extra-glandular manifestations [1]. Currently there is no definitive diagnostic test, and the immuno-pathology is not fully understood. Recently focus has shifted to investigating microRNAs (miRs) in an effort to understand the mechanism...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1996

ISSN: 0003-4967

DOI: 10.1136/ard.55.7.450